Recent Developments In Patient-SpecificImage-Based Modeling Of Hemodynamics

Abstract

Current challenges in patient-specific computational hemodynamics include
validation of the numerical models with in vivo data, the use of numerical models in large
clinical studies, and the simulation of blood flow patterns in presence of endovascular
devices. This paper summarizes some of the recent advances in each of these research
directions. In particular, the following studies are described: validation of blood flow
dynamics in carotid arteries using magnetic resonance and Doppler ultrasound, clinical study
of rupture of cerebral aneurysms and relationship to intraaneurysmal flow patterns, and
simulation of flow alterations into cerebral aneurysms due to implantation of stents and coils.
This paper shows that accurate patient-specific hemodynamic models can be constructed from
medical image data, and can be used for large clinical studies.